Botanical Center Plants
Botanical Profiles | Scientific Summaries of the Investigated Plants Heading link
The Botanical Center Plants | 21 Plants Associated with Female Health Heading link
Over the course of the entire P50 project, the UIC Botanical Center has studied 20 different botanicals, many of them extensively. All plants have a scientific track record and documented use as dietary supplements for women’s health. The following four plants were investigated most intensively by all three Center Projects and four Center Cores.
- Actaea racemosa L. (Black Cohosh)
- Glycyrrhiza glabra L. (Licorice; glabra species)
- Humulus lupulus L. (Hops)
- Trifolium pratense L. (Red Clover)
For these four plants, chemically and biologically standardized botanical products were developed and used in three Phase I , one Phase II, and three Herb-Drug Interaction clinical trials. Furthermore, the following plants were studied in detail with regard to their phytochemical composition, their biological activity profiles, and the ADME properties of their constituents:
- Angelica sinensis L. (Dang Gui)
- Dioscorea villosa THUNB. (Wild Yam)
- Glycyrrhiza inflata L. (Licorice; inflata species)
- Glycyrrhiza uralensis Fisch. ex DC (Licorice; uralensis species)
- Piscidia erythrina L. (Jamaican Dogwood)
- Pueraria mirifica L. (Kwao Keur)
- Rhodiola rosea L. (Roseroot)
- Silybum marianum L. (Milk Thistle)
- Valeriana officinalis L. (Valerian)
- Vaccinium macrocarpon (Cranberry)
- Viburnum opulus L. (Guelder Rose)
- Viburnum prunifolium L. (Blackhaw)
- Vitex agnus-castus L. (Chasteberry)
Finally, the following plants were studied for as part of the evaluation of complex, multi-component botanicals:
- Asclepias tuberosa L. (Butterfly Milkweed)
- Chamaelirium luteum (L.) A. GRAY (Fairywand)
- Gentiana lutea L. (Gentian)
- Taraxacum officinale WEBER (Dandelion)